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Researchers have identified two common genetic mutations that increase the risk of osteoporosis and related bone fractures, according to a study released Tuesday.

These changes were present in 20 percent of the people studied and highlight the potential role of screening for osteoporosis, the bone-thinning disease that mainly affects women after menopause, they said in the journal Lancet.

''Eventually, a panel of genetic markers could be used in addition to environmental risk factors to identify individuals who are most at risk for osteoporotic fractures,'' wrote Tim Spector and Brent Richards, researchers at King's College London.

Osteoporosis is a condition in which bone density thins as more bone cells are lost than replaced when people age.

It affects about one in three women and one in five men around the world, according to the International Osteoporosis Foundation.

Drugs called bisphosphonates are used primarily to increase bone mass and cut the risk of fractures in patients with osteoporosis.

These include Fosamax, produced by Merck & Company, which American researchers on Monday showed could increase the risk of a type of abnormal heartbeat.

In the Lancet study, the team scanned the genes of 2,094 female twins and identified a link between decreased bone mineral density and changes in chromosomes 8 and 11.

In chromosome 11, the change was associated with a 30 percent increased risk of the condition and related fractures, and for chromosome 8, the mutation raised risk by 20 percent.

For people who had both changes, their risk went up by 30 percent.

These two genes are important targets for treatments, and drugs are already under development, the researchers said.

President Jimmy Carter was the first President of the United States of America to have officially reported the UFO he saw to the authorities. He was also the President who said that if elected he would see that UFO-Alien Full Disclosure would take place. That the American public would be told the truth about everything was one of the campaign cries of Jimmy Carter. Carter made a promise he could not or would not be able to keep.

After Carter won the White House, he paid a visit to the then-CIA Director, George Bush. Carter had an interest in UFOs ever since experiencing his first sighting sometime in 1969 while standing outside a Lion's Club in Georgia. http://louis-j-sheehan-esquire.us/page1.aspx
His campaign speeches promising to unravel the government's long held cover-up was the "Parting of the Red Sea" for Ufologists not only in America but around the world. Here was the one guy who would open up the "Promised Land" and lead them into Full Disclosure.

Carter wanted the U.S. Government's UFO secret documents declassified. George Bush more or less told Carter that the President of the United States did not have the need to know the information contained in those documents. Can you even begin to imagine that? What lends even more mind-blowing credibility to this alleged event between Carter and Bush is the credibility of the allegation maker: Daniel Sheehan.

Daniel Sheehan was born in1946 and graduated from Harvard Law School. There, he was co-founder of the Harvard Civil Rights and Civil Liberty Law Review. He went on to work for the American Civil Liberties Union and became general counsel for a host of entities including The Disclosure Project-a group dedicated to getting the U.S. Government to allow full and unfettered access to what the Feds know about the UFO-Alien phenomenon.

According to Sheehan, Bush Senior, who was the CIA Director, refused Carter's request for disclosure of the UFO documents, even to the President of the United States, because it was generally believed in the halls and corridors of the secret, black-ops government that Carter would then turn the truth over to the American people.

Director of a California think tank, Sheehan's credentials are impeccable. Sheehan's career is a litany of high-profile cases like, "legal counsel team for the New York Times' Pentagon Papers case, defense of the Berrigan brothers, going after the Kerr-McGee nuclear plant (Karen Silkwood), Three-Mile Island, Iran-Contra. At the Disclosure Conference, Sheehan says the Bush-Carter story was relayed to him in 1977 by Marcia Smith of the Congressional Research Service, part of the Library of Congress."

Sheehan's interest in this phenomenon came about when Sheehan met Marcia Smith through a mutual acquaintance. Smith told Sheehan that she was involved in a research project for the Science and Technology Committee of the Library of Congress that would address the issues of the potential existence of extraterrestrial intelligence and make an evaluation of the data on the phenomena of UFOs. When Sheehan queried Smith as to who exactly wanted this study done, her answer was none other than Jimmy Carter.

This all was with a view to investigate exactly what could or could not be turned over to the general public, according to Daniel Sheehan.

Smith asked Sheehan if he could, since he was the then-General Counsel to United States Jesuit Headquarters at their National Office in Washington D.C., get access to the records on the UFO-Alien issue contained in the Vatican. Though Sheehan made repeated attempts to gain access to the Vatican's documents through official channels, he was refused each time. http://louis-j-sheehan-esquire.us/


This makes one wonder just why, if all there is to this UFO-Alien issue is weather balloons, flocks of geese, and swamp gas, would the Vatican (or any government on the earth, for that matter) have top-secret, and highly unattainable records pertaining to a nonexistent issue?

After telling Marcia Smith of his roadblock with the Vatican Library, she asked if he could help with a team that was lobbying Congressional leader to reinstate funds for the SETI (Search For Extraterrestrial Intelligence) program. Sheehan indicated to Smith that he was glad to help out. Smith also later asked him if he could help out with an investigation into "the potential theological religious implications of potential contact with extraterrestrial civilizations."

This again begs the question that if there's nothing at all to this phenomenon, then why this study?

Sheehan agreed to Smith's request but insisted he have access to the documents pertaining to this issue that she had garnered for an investigation she did for the Science and Technology Committee in Congress. When asked what exactly Sheehan wanted to see, he indicated he wanted access to "the classified sections of the Project Blue Book."

Astoundingly, Daniel was granted access.

He was not allowed to take notes, photos, or carry anything into the room containing the documents or out with him when he left the Library of Congress where the documents were stored. After proceeding through multiple layers of security, he was shown to the room with microfiche machines. Before entering, he was told he could not take his briefcase with him. Almost absent-mindedly, he had a yellow legal pad under his arm that wasn't confiscated before he entered the room. He proceeded through small canisters of film. It didn't take long to find proof.

He discovered photos of what appeared to be a disc-shaped craft. It had crashed.

"It had hit into this field and had dug up, kind of plowed this kind of trough through this field. It was wedged into the side of this bank. There was snow all around the picture. The vehicle was wedged into the side of this mud-like embankment -- kind of up at an angle."

The men taking photos were unmistakably, in Sheehan's mind, American Air Force personnel.

As Sheehan continued to review the film, he discovered a close-up of the craft that revealed symbols or glyphs written on the craft. He thought it was an insignia. He wanted to record what he saw, but remembered he was not allowed to take notes. He knew it was likely his legal pad would be discovered when he left the room and the guards would examine it to see if he had taken notes. http://louis-j-sheehan.org/
However, since he wanted those insignias, he had to find a way to record them. He decided to arrange the cardboard backing of his legal pad in such a way against the microfiche screen so he could trace the symbols. When he left the top-secret document room, he was searched. His pad was taken and flipped through for notes. Finding none, and not noticing the traced symbols on the cardboard backing of the yellow pad, it was returned to him by the guards and Sheehan left.

Sheehan not only revealed to Marcia Smith what he had found but he also revealed the information to his boss at the Jesuit National Headquarters. Meetings and conventions were convened on the issue. Reports were written. President Carter saw at least one of the reports made by Marcia Smith, which included information from Daniel Sheehan's discoveries.

Sheehan still has the yellow notepad with the symbols but says no analysis has been done on the symbols.

Oh, are you wondering about the reports Marcia Smith finished after Daniel Sheehan's discovery and what they said? Well, Sheehan read them and according to Sheehan:

"The one report that Marcia showed me on extraterrestrial phenomena actually stated that it was the conclusion of the Library of Congress, Science and Technology Division, that from two to six, at least, other highly-intelligent, technologically-developed civilizations exist right within our own galaxy." [sources]

"The second report," says Sheehan, "they had drawings of different shapes of UFOs that have been sighted," continued Sheehan. "They didn't site any particular cases, but they said that they believed there was a significant number of instances where the official United States Air Force investigations were unable to discount the possibility that one or more of these vehicles was actually from one of these extraterrestrial civilizations. They put this together, and sent it over to the President. I ended up seeing a copy of it."

The Carter Administration, though not bringing about Full Disclosure, had a very busy four years of UFO phenomena. I can't help but wonder if he had had another term in office, what could have come of all of this?



    

If there's a skill or process you want to learn or know more about, chances are there's an online video for it. These days you can find a video that will teach you to cook, survive college, build your own headphones or even become a better kisser.

This week, I took a look at just a few Web sites that make finding these videos easy, including Howcast Media Inc.'s Howcast.com1, WonderHowTo.com2 from WonderHowTo Inc. and eHow Inc.'s eHow.com3. Howcast.com, which launched in February, encourages users to make and share good-quality, entertaining videos by providing tools on its site, and has about 5,000 videos so far. WonderHowTo.com, launched in January, used a different strategy by aggregating over 110,000 videos from various sources -- including Howcast, YouTube and Scripps Networks -- rather than publishing its own content. EHow, a site that started in 1999 with text-only content, contains over 100,000 instructional articles submitted by its users or eHow editors, and has a small catalog of videos. http://louis1j1sheehan1esquire.us/page1.aspx


Howcast videos can be seen in full-screen mode using a player that illustrates step-by-step text instructions beside video screens.

After testing each of these sites, I found that my favorite how-to videos had steps that were clearly labeled and numbered and the ability to fast forward to or play back specific parts in the video -- tools that Howcast included in almost all of its videos. At least some of the videos on the three sites simply illustrate things you could likely figure out how to do without watching a video, such as "How to Make Green Beer." (Add food coloring.) Howcast.com and WonderHowTo both require users to sign in, which confirms their date of birth, before looking at what they consider "mature" content.

These three free sites are advertisement-supported, and Howcast's ads run alongside videos. WonderHowTo.com runs ads at the top and side of its own site, on which it will play certain videos. But because videos on WonderHowTo come from other sources, those other sites can show video-embedded ads according to their rules. EHow's videos run pop-up text advertisements displaying names and links of other related (and sometimes unrelated) Web sites. But I couldn't get the pop-up ads to stay closed.

Overall, I preferred the look of Howcast's site and its well-organized videos. But its content paled in comparison to WonderHowTo's 110,000 videos and even eHow's 100,000 instructional articles. WonderHowTo.com does a nice job of gathering content from across the Web, though the inconsistencies of other sites (including advertisements, layout and video player) were a bit frustrating. EHow's articles were useful, as were its few videos, but I couldn't get over the site's unyielding video pop-up ads.

Howcast.com's content was informative with an amusing edge, including a video titled "How to Tell If Your Boyfriend's A Psycho."(If he calls 50 times a day, for example.) Other videos on the site are more serious, like "How to Make Sushi" by an executive sushi chef in New York City.

The founders of Howcast Media formerly worked in Google's video department, including during the acquisition of YouTube. All of Howcast's content comes from one of four sources: written and produced by Howcast in its studios; emerging filmmakers who apply and are accepted into the Howcast Directors Program to receive $50 a video and 50% of the advertising revenue generated from videos that generate over 40,000 views on the site; content partners like Popular Science; and Howcast users' personal how-to videos.

In order to make it easier for average users to upload better-looking videos, Howcast provides an Upload and Enhance tool that simply and quickly adds professional-looking graphics and printable steps to go along with how-to videos. This formula makes videos more enjoyable to watch. http://louis1j1sheehan1esquire.us/


Videos made in the Howcast Studios include accompanying music, good narratives and actors who add humor to an otherwise humdrum how-to. Among its helpful features is a video player that has smart blue markers to show where facts are sprinkled throughout the video and green markers to illustrate where tips appear. For example, the fact at the end of a video for beginner guitarists called "How to Play a Basic Bar Chord" is "The late Kurt Cobain claimed he was trying to rip off the Pixies when he wrote 'Smells Like Teen Spirit. '" In full-screen view, users can zoom in on any part of a video, and written-out steps and thumbnail stills of the scene appear to the right of the screen.

Howcast tries to run ads alongside videos that relate to the content. A video titled "How To Clean Your Dog's Teeth" has an ad for PetSmart Stores running on its page.

WonderHowTo.com was developed by a former television executive with the intention of using the site to produce its own video, like Howcast.com. Instead, WonderHowTo.com opted to tap the vast selection of how-to videos already available on the Web.

A Browse button pulls down 35 categories from which users can sort content, including Spirituality, Dating & Relationships and Fitness. In the Fashion subcategory under Beauty & Style, I found 290 videos including one on "How to Tie a Windsor Knot" and another titled "How to Turn Old Underpants Into a Bra" -- neither of which I'll be using anytime soon. Other categories include Clip of the Day, Recommendations (for users who are logged in) and Fresh, where new videos are listed. Users can grade videos to help others tell which they think are the best, and a Top Grade category compiles the top-ranked videos.

WonderHowTo's content comes from over 700 sites, according to the company. I used the site to find a video on YouTube about how to do a front-flip, clips on VideoJug.com that provided terrific tennis tips from a coach, and a video from EasyBarTricks.com about how to stick a beer bottle to a wall without glue or gum. (Hint: You'll need a corner and a wall you don't mind marking up.) WonderHowTo made it easier to find these videos than by performing a general search on the Web.

I submitted a non-how-to video to this site by simply entering a URL, without logging in. I never found the video I submitted on the site; WonderHowTo explained that it screens all videos prior to posting them, so it must have found my video.

EHow.com uses its database of articles to encourage people to watch videos, when they're relevant. This site uses calm, pastel colors to give a relaxed feeling -- especially compared with WonderHowTo, where banner ads surround the page. EHow's 26 categories include Parenting, Parties & Entertaining and Weddings. Twelve subcategories within Weddings led to 23 articles about Bridal Party Responsibilities -- a popular topic was "How To Deal With a Bridezilla." Related videos, such as "How To Get Rid of Wedding Day Jitters," ran along the right of the page. http://louis-j-sheehan.org/page1.aspx



Videos can also be found on eHow within a marked tab at the top of the page. But unlike the articles on eHow, these videos weren't well organized or as easily searchable. I watched one of eHow's Featured Videos called "How to Know if Your Toe Is Broken," but after closing a pop-up ad for UPS during Step One of the video, another ad popped up during Step Five. Neither ad had anything to do with broken toes.

But the eHow videos were professional-looking and included quite a few tips that I didn't know. That broken toe video was submitted by the eHow Health Editor, and a link at the top of the page led me to hundreds of other health-related articles. I found another video on "How To Remove Wallpaper," which was posted by the Home & Garden Editor and included a list of things I would need to proceed, along with numbered steps.

It isn't always easy to learn from the information you find online, and how-to videos can be a big help -- especially when they're well-made and easy to find using one of these sites. Howcast.com has well-presented content that was enjoyable to watch, but WonderHowTo.com offers a better variety of instructional videos.